Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis

Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis

Systemic sclerosis (SSc, scleroderma) is a connective tissue disease of unknown etiology that affects particularly the skin. Early stages of SSc are characterized by vascular changes and inflammatory infiltrates in the lesional skin.