Pharmacologic Induction of Heme Oxygenase 1 Reduces Acute Inflammatory Arthritis in Mice

The recurrence and the intensity of the acute phase of joint inflammation are important factors in the destruction of adjacent cartilage and bone in inflammatory forms of human arthritis, such as acute gout and pseudogout, infectious arthritis, seronegative spondylarthritides, rheumatoid arthritis, and juvenile arthritis.