Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study

Systemic sclerosis (SSc) is an orphan and incurable connective tissue disease characterised by vascular, immune and fibrotic abnormalities in the skin and
some internal organs. It involves progressive organ failure, and it is therefore a severe chronic disease leading to major disability and even premature  death.

RMDs are highly prevalent and significantly affect activity limitations and participation restrictions. More effort is needed to improve care and research in this field.