Development and validation of a scale for mouth handicap in systemic sclerosis: the Mouth Handicap in Systemic Sclerosis scale

Systemic sclerosis (SSc) is a connective-tissue disease characterised by excessive collagen deposition and by vascular hyper-reactivity and obliterative microvascular phenomena.1 2 SSc is responsible for skin, tendon, joint and vessel damage, which leads to handicap.3