Eugénie Koumakis Archives - Hôpital Cochin

14 Sep Candidate Gene Study in Systemic Sclerosis Identifies a Rare and Functional Variant of the TNFAIP3 Locus as a Risk Factor for Polyautoimmunity

Posted at 19:22h in Eugénie Koumakis, Publi-Rhumato-a

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Evidence of a shared pathogenic basis across connective tissue diseases (CTDs) is provided by familial and individual aggregation of autoimmune diseases and by the well-known pleiotropism of autoimmune susceptibility genes. [/vc_column_text][vc_separator type="transparent" thickness="5" up="10" down="10"][vc_column_text] [button size='medium' style='' text='Télécharger la publication'...

14 Sep A Regulatory Variant in CCR6 Is Associated With Susceptibility to Antitopoisomerase-Positive Systemic Sclerosis

Posted at 19:19h in Eugénie Koumakis, Publi-Rhumato-a

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Systemic sclerosis (SSc) is a chronic systemic disease with a complex pathogenesis. The disease is characterized by early vascular alterations and activation of the immune system, with autoimmune features preceding the deposition of extracellular matrix, leading to systemic fibrosis. [/vc_column_text][vc_separator...

14 Sep Bone Mineral Density Evolution After Successful Parathyroidectomy in Patients With Normocalcemic Primary Hyperparathyroidism

Posted at 19:16h in Eugénie Koumakis, Publi-Rhumato-a

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Skeletal involvement, especially on cortical bone, is a hallmark of primary hyperparathyroidism (PHPT). After successful parathyroidectomy (PTX), increases in bone mineral density (BMD), both in symptomatic and in mild asymptomatic PHPT have been demonstrated. [/vc_column_text][vc_separator type="transparent" thickness="5" up="10" down="10"][vc_column_text] [button size='medium'...

14 Sep Individual site-specific bone mineral density gain in normocalcemic primary hyperparathyroidism

Posted at 19:13h in Eugénie Koumakis, Publi-Rhumato-a

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Normocalcemic primary hyperparathyroidism (PHPT) is characterized by normal serum calcium levels, and the exclusion of causes of secondary hyperparathyroidism. [/vc_column_text][vc_separator type="transparent" thickness="5" up="10" down="10"][vc_column_text] [button size='medium' style='' text='Télécharger la publication' icon='fa-download' icon_color='' link='https://www.cochin-poa.com/wp-content/uploads/2015/09/publication-rhumatologie-A-4.pdf' target='_blank' color='' hover_color='' border_color='' hover_border_color='' background_color='' hover_background_color=''...

14 Sep Trabecular Bone Score in Female Patients with Systemic Sclerosis: Comparison with Rheumatoid Arthritis and Influence of Glucocorticoid Exposure

Posted at 19:10h in Eugénie Koumakis, Publi-Rhumato-a

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Osteoporosis (OP) and fractures are major causes of morbidity in subjects with rheumatic inflammatory diseases. The etiology of bone loss in rheumatic diseases is multifactorial, involving age, disability, low body mass index (BMI), longstanding disease, disease-related systemic inflammation, and...