Bone Mineral Density Evolution After Successful Parathyroidectomy in Patients With Normocalcemic Primary Hyperparathyroidism

Bone Mineral Density Evolution After Successful Parathyroidectomy in Patients With Normocalcemic Primary Hyperparathyroidism

Skeletal involvement, especially on cortical bone, is a hallmark of primary hyperparathyroidism (PHPT). After successful parathyroidectomy (PTX), increases in bone mineral density (BMD), both in symptomatic and in mild asymptomatic PHPT have been demonstrated.

Osteoporosis (OP) and fractures are major causes of morbidity in subjects with rheumatic inflammatory diseases. The etiology of bone loss in rheumatic diseases is multifactorial, involving age, disability, low body mass index (BMI), longstanding disease, disease-related systemic inflammation, and longterm glucocorticoid (GC) exposure.